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β-Amyloid-Induced Neuronal Apoptosis Involves c-Jun N-Terminal Kinase-Dependent Downregulation of Bcl-w

β-Amyloid protein (Aβ) has been implicated as a key molecule in the neurodegenerative cascades of Alzheimer's disease (AD). Aβ directly induces neuronal apoptosis, suggesting an important role of Aβ neurotoxicity in AD neurodegeneration. However, the mechanism(s) of Aβ-induced neuronal apoptosi...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Yao, Mingzhong, Nguyen, Thuy-Vi V., Pike, Christian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725978/
https://ncbi.nlm.nih.gov/pubmed/15689551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4736-04.2005
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