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Brain-Derived Neurotrophic Factor and Antidepressant Drugs Have Different But Coordinated Effects on Neuronal Turnover, Proliferation, and Survival in the Adult Dentate Gyrus

Antidepressants increase proliferation of neuronal progenitor cells and expression of brain-derived neurotrophic factor (BDNF) in the hippocampus. We investigated the role of BDNF signaling in antidepressant-induced neurogenesis by using transgenic mice with either reduced BDNF levels (BDNF(+/-)) or...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Sairanen, Mikko, Lucas, Guilherme, Ernfors, Patrik, Castrén, Maija, Castrén, Eero
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2005
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725966/
https://ncbi.nlm.nih.gov/pubmed/15689544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3741-04.2005
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