Activation of the TrkB Neurotrophin Receptor Is Induced by Antidepressant Drugs and Is Required for Antidepressant-Induced Behavioral Effects

Recent studies have indicated that exogenously administered neurotrophins produce antidepressant-like behavioral effects. We have here investigated the role of endogenous brain-derived neurotrophic factor (BDNF) and its receptor trkB in the mechanism of action of antidepressant drugs. We found that...

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Pubblicato in:J Neurosci
Autori principali: Saarelainen, Tommi, Hendolin, Panu, Lucas, Guilherme, Koponen, Eija, Sairanen, Mikko, MacDonald, Ewen, Agerman, Karin, Haapasalo, Annakaisa, Nawa, Hiroyuki, Aloyz, Raquel, Ernfors, Patrik, Castrén, Eero
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742146/
https://ncbi.nlm.nih.gov/pubmed/12514234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-01-00349.2003
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