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Selective Loss of BDNF in the Dentate Gyrus Attenuates Antidepressant Efficacy

BACKGROUND: Brain-derived neurotrophic factor (BDNF) plays an important role in neural plasticity in the adult nervous system and has been suggested as a target gene for antidepressant treatment. The neurotrophic hypothesis of depression suggests that loss of BDNF from the hippocampus contributes to...

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Bibliografische gegevens
Hoofdauteurs: Adachi, Megumi, Barrot, Michel, Autry, Anita E., Theobald, David, Monteggia, Lisa M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2352150/
https://ncbi.nlm.nih.gov/pubmed/17981266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2007.09.019
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