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Selective Loss of BDNF in the Dentate Gyrus Attenuates Antidepressant Efficacy
BACKGROUND: Brain-derived neurotrophic factor (BDNF) plays an important role in neural plasticity in the adult nervous system and has been suggested as a target gene for antidepressant treatment. The neurotrophic hypothesis of depression suggests that loss of BDNF from the hippocampus contributes to...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2352150/ https://ncbi.nlm.nih.gov/pubmed/17981266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2007.09.019 |
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