N-Terminal Insertion and C-Terminal Ankyrin-Like Repeats of α-Latrotoxin Are Critical for Ca(2)+-Dependent Exocytosis

α-Latrotoxin, a potent stimulator of exocytosis from neurons and neuroendocrine cells, has been studied intensively, but the mechanisms of its actions are poorly understood. Here, we developed a new method to generate active recombinant α-latrotoxin and conducted a structure/function analysis of the...

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Vydáno v:J Neurosci
Hlavní autoři: Li, Gang, Lee, David, Wang, Li, Khvotchev, Mikhail, Chiew, Soon Kwang, Arunachalam, Lakshmanan, Collins, Tony, Feng, Zhong-Ping, Sugita, Shuzo
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2005
Témata:
Cellular/Molecular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725796/
https://ncbi.nlm.nih.gov/pubmed/16267226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3560-05.2005
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