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NMDA Receptor Activation Inhibits α-Secretase and Promotes Neuronal Amyloid-β Production
Acute brain injuries have been identified as a risk factor for developing Alzheimer's disease (AD). Because glutamate plays a pivotal role in these pathologies, we studied the influence of glutamate receptor activation on amyloid-β (Aβ) production in primary cultures of cortical neurons. We fou...
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| Udgivet i: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6725703/ https://ncbi.nlm.nih.gov/pubmed/16221845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0849-05.2005 |
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