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Zn(2+) Inhibits Mitochondrial Movement in Neurons by Phosphatidylinositol 3-Kinase Activation

Mitochondria have been identified as targets of the neurotoxic actions of zinc, possibly through decreased mitochondrial energy production and increased reactive oxygen species accumulation. It has been hypothesized that impairment of mitochondrial trafficking may be a mechanism of neuronal injury....

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Опубликовано в: :J Neurosci
Главные авторы: Malaiyandi, Latha M., Honick, Anthony S., Rintoul, Gordon L., Wang, Qiming J., Reynolds, Ian J.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725691/
https://ncbi.nlm.nih.gov/pubmed/16221861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0868-05.2005
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