Strong Calcium Entry Activates Mitochondrial Superoxide Generation, Upregulating Kinase Signaling in Hippocampal Neurons

Large increases in cytosolic free Ca(2+) ([Ca(2+)](i)) activate several kinases that are important for neuronal plasticity, including Ca(2+)/calmodulin-dependent kinase II (CaMKII), protein kinase A (PKA), and protein kinase C (PKC). Because it is also known, mainly in non-neuronal systems, that sup...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hongpaisan, Jarin, Winters, Christine A., Andrews, S. Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730216/
https://ncbi.nlm.nih.gov/pubmed/15574738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3278-04.2004
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