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Coupling diverse routes of calcium entry to mitochondrial dysfunction and glutamate excitotoxicity
Overactivation of NMDA receptors (NMDARs) is a critical early step in glutamate-evoked excitotoxic injury of CNS neurons. Distinct NMDAR-coupled pathways specified by, for example, receptor location or subunit composition seem to govern glutamate-induced excitotoxic death, but there is much uncertai...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701040/ https://ncbi.nlm.nih.gov/pubmed/19482936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903546106 |
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