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Coupling diverse routes of calcium entry to mitochondrial dysfunction and glutamate excitotoxicity
Overactivation of NMDA receptors (NMDARs) is a critical early step in glutamate-evoked excitotoxic injury of CNS neurons. Distinct NMDAR-coupled pathways specified by, for example, receptor location or subunit composition seem to govern glutamate-induced excitotoxic death, but there is much uncertai...
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Hoofdauteurs: | , , , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
National Academy of Sciences
2009
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701040/ https://ncbi.nlm.nih.gov/pubmed/19482936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903546106 |
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