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Differential NMDA receptor-dependent calcium loading and mitochondrial dysfunction in CA1 vs. CA3 hippocampal neurons

Hippocampal CA1 pyramidal neurons are selectively vulnerable to ischemia, while adjacent CA3 neurons are relatively resistant. Although glutamate receptor-mediated mitochondrial Ca(2+) overload and dysfunction is a major component of ischemia-induced neuronal death, no direct relationship between se...

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Detalhes bibliográficos
Main Authors: Stanika, Ruslan I., Winters, Christine A., Pivovarova, Natalia B., Andrews, S. Brian
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818520/
https://ncbi.nlm.nih.gov/pubmed/19879359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.10.020
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