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Coupling diverse routes of calcium entry to mitochondrial dysfunction and glutamate excitotoxicity

Overactivation of NMDA receptors (NMDARs) is a critical early step in glutamate-evoked excitotoxic injury of CNS neurons. Distinct NMDAR-coupled pathways specified by, for example, receptor location or subunit composition seem to govern glutamate-induced excitotoxic death, but there is much uncertai...

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書誌詳細
主要な著者: Stanika, Ruslan I., Pivovarova, Natalia B., Brantner, Christine A., Watts, Charlotte A., Winters, Christine A., Andrews, S. Brian
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2701040/
https://ncbi.nlm.nih.gov/pubmed/19482936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903546106
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