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Inhibitors of the Mitogen-Activated Protein Kinase Kinase 1/2 Signaling Pathway Clear Prion-Infected Cells from PrP(Sc)

Prions represent a unique class of infectious agents in which the normal cellular prion protein (PrP(C)) is converted to an abnormal isoform (PrP(Sc)), which accumulates in the brain and constitutes the major, if not the only, component of the infectious particle. Factors that still remain to be ide...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Nordström, Elin K., Luhr, Katarina M., Ibáñez, Carlos, Kristensson, Krister
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725673/
https://ncbi.nlm.nih.gov/pubmed/16162927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2349-05.2005
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