Inhibitors of the Mitogen-Activated Protein Kinase Kinase 1/2 Signaling Pathway Clear Prion-Infected Cells from PrP(Sc)

Prions represent a unique class of infectious agents in which the normal cellular prion protein (PrP(C)) is converted to an abnormal isoform (PrP(Sc)), which accumulates in the brain and constitutes the major, if not the only, component of the infectious particle. Factors that still remain to be ide...

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Bibliografiska uppgifter
I publikationen:J Neurosci
Huvudupphovsmän: Nordström, Elin K., Luhr, Katarina M., Ibáñez, Carlos, Kristensson, Krister
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2005
Ämnen:
Neurobiology of Disease
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725673/
https://ncbi.nlm.nih.gov/pubmed/16162927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2349-05.2005
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