Abnormal Long-Lasting Synaptic Plasticity and Cognition in Mice Lacking the Mental Retardation Gene Pak3

Mutations in the Pak3 gene lead to nonsyndromic mental retardation characterized by selective deficits in cognition. However, the underlying mechanisms are yet to be elucidated. We report here that the knock-out mice deficient in the expression of p21-activated kinase 3 (PAK3) exhibit significant ab...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Meng, Jinsong, Meng, Yanghong, Hanna, Amanda, Janus, Christopher, Jia, Zhengping
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2005
Fag:
Development/Plasticity/Repair
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725420/
https://ncbi.nlm.nih.gov/pubmed/16014725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0028-05.2005
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