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Abnormal Long-Lasting Synaptic Plasticity and Cognition in Mice Lacking the Mental Retardation Gene Pak3

Mutations in the Pak3 gene lead to nonsyndromic mental retardation characterized by selective deficits in cognition. However, the underlying mechanisms are yet to be elucidated. We report here that the knock-out mice deficient in the expression of p21-activated kinase 3 (PAK3) exhibit significant ab...

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Publicado en:J Neurosci
Autores principales: Meng, Jinsong, Meng, Yanghong, Hanna, Amanda, Janus, Christopher, Jia, Zhengping
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725420/
https://ncbi.nlm.nih.gov/pubmed/16014725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0028-05.2005
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