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Spinal G-Protein-Gated Potassium Channels Contribute in a Dose-Dependent Manner to the Analgesic Effect of μ- and δ- But Not κ-Opioids

Opioids can evoke analgesia by inhibiting neuronal targets in either the brain or spinal cord, and multiple presynaptic and postsynaptic inhibitory mechanisms have been implicated. The relative significance of presynaptic and postsynaptic inhibition to opioid analgesia is essentially unknown, as are...

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Vydáno v:J Neurosci
Hlavní autoři: Marker, Cheryl L., Luján, Rafael, Loh, Horace H., Wickman, Kevin
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725379/
https://ncbi.nlm.nih.gov/pubmed/15814785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4899-04.2005
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