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Spinal G-Protein-Gated Potassium Channels Contribute in a Dose-Dependent Manner to the Analgesic Effect of μ- and δ- But Not κ-Opioids

Opioids can evoke analgesia by inhibiting neuronal targets in either the brain or spinal cord, and multiple presynaptic and postsynaptic inhibitory mechanisms have been implicated. The relative significance of presynaptic and postsynaptic inhibition to opioid analgesia is essentially unknown, as are...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Marker, Cheryl L., Luján, Rafael, Loh, Horace H., Wickman, Kevin
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725379/
https://ncbi.nlm.nih.gov/pubmed/15814785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4899-04.2005
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