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Opioid ligands with mixed μ/δ opioid receptor interactions: An emerging approach to novel analgesics
Opioids are widely used in the treatment of severe pain. The clinical use of the opioids is limited by serious side effects such as respiratory depression, constipation, development of tolerance, and physical dependence and addiction liabilities. Most of the currently available opioid analgesics exe...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer-Verlag
2006
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2751430/ https://ncbi.nlm.nih.gov/pubmed/16584118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080114 |
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