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Ligand requirements for involvement of PKCε in synergistic analgesic interactions between spinal μ and δ opioid receptors
BACKGROUND AND PURPOSE: We recently found that PKCε was required for spinal analgesic synergy between two GPCRs, δ opioid receptors and α(2)(A) adrenoceptors, co-located in the same cellular subpopulation. We sought to determine if co-delivery of μ and δ opioid receptor agonists would similarly resu...
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| Publicado no: | Br J Pharmacol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292975/ https://ncbi.nlm.nih.gov/pubmed/24827408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12774 |
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