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Heteromerization of the μ- and δ-Opioid Receptors Produces Ligand-Biased Antagonism and Alters μ-Receptor Trafficking

Heteromerization of opioid receptors has been shown to alter opioid receptor pharmacology. However, how receptor heteromerization affects the processes of endocytosis and postendocytic sorting has not been closely examined. This question is of particular relevance for heteromers of the μ-opioid rece...

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Bibliographic Details
Main Authors: Milan-Lobo, Laura, Whistler, Jennifer L.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097170/
https://ncbi.nlm.nih.gov/pubmed/21422164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.179093
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