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Efficacy and ligand bias at the μ-opioid receptor

In order to describe drug action at a GPCR, a full understanding of the pharmacological terms affinity, efficacy and potency is necessary. This is true whether comparing the ability of different agonists to produce a measurable response in a cell or tissue, or determining the relative ability of an...

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Detalhes bibliográficos
Autor principal: Kelly, E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724102/
https://ncbi.nlm.nih.gov/pubmed/23646826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12222
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