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Plasmalemmal Phosphatidylinositol-4,5-Bisphosphate Level Regulates the Releasable Vesicle Pool Size in Chromaffin Cells

During exocytosis, certain phospholipids may act as regulators of secretion. Here, we used several independent approaches to perturb the phosphatidylinositol-4,5-bisphosphate [PI(4,5)P(2)] level in bovine chromaffin cells to investigate how changes of plasmalemmal PI(4,5)P(2) affect secretion. Membr...

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Pubblicato in:J Neurosci
Autori principali: Milosevic, Ira, Sørensen, Jakob B., Lang, Thorsten, Krauss, Michael, Nagy, Gábor, Haucke, Volker, Jahn, Reinhard, Neher, Erwin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725155/
https://ncbi.nlm.nih.gov/pubmed/15758165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3761-04.2005
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