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Functional Recovery from Desensitization of Vanilloid Receptor TRPV1 Requires Resynthesis of Phosphatidylinositol 4,5-Bisphosphate

Capsaicin and other naturally occurring pungent molecules have long been used as topical analgesics to treat a variety of chronic pain conditions. The analgesic effects of these compounds involve long-term desensitization of nociceptors after strong stimulation. To elucidate the underlying mechanism...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Liu, Beiying, Zhang, Chunguang, Qin, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724779/
https://ncbi.nlm.nih.gov/pubmed/15888659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1296-05.2005
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