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Functional Control of Cold- and Menthol-Sensitive TRPM8 Ion Channels by Phosphatidylinositol 4,5-Bisphosphate

Cold is detected by a small subpopulation of peripheral thermoreceptors. TRPM8, a cloned menthol- and cold-sensitive ion channel, has been suggested to mediate cold transduction in the innocuous range. The channel shows a robust response in whole-cell recordings but exhibits markedly reduced activit...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Liu, Beiying, Qin, Feng
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725927/
https://ncbi.nlm.nih.gov/pubmed/15716403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3632-04.2005
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