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Functional Control of Cold- and Menthol-Sensitive TRPM8 Ion Channels by Phosphatidylinositol 4,5-Bisphosphate
Cold is detected by a small subpopulation of peripheral thermoreceptors. TRPM8, a cloned menthol- and cold-sensitive ion channel, has been suggested to mediate cold transduction in the innocuous range. The channel shows a robust response in whole-cell recordings but exhibits markedly reduced activit...
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| Published in: | J Neurosci |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Society for Neuroscience
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6725927/ https://ncbi.nlm.nih.gov/pubmed/15716403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3632-04.2005 |
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