Ca(2+)-Dependent Desensitization of TRPV2 Channels Is Mediated by Hydrolysis of Phosphatidylinositol 4,5-Bisphosphate

TRPV2 is a member of the transient receptor potential family of ion channels involved in chemical and thermal pain transduction. Unlike the related TRPV1 channel, TRPV2 does not appear to bind either calmodulin or ATP in its N-terminal ankyrin repeat domain. In addition, it does not contain a calmod...

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Main Authors: Mercado, Jose, Gordon-Shaag, Ariela, Zagotta, William N., Gordon, Sharona E.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2010
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001133/
https://ncbi.nlm.nih.gov/pubmed/20926660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2108-10.2010
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