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Resynthesis of phosphatidylinositol 4,5-bisphosphate mediates adaptation of the caffeine response in rat taste receptor cells

Caffeine, a prototypic bitter stimulus, produces several physiological actions on taste receptor cells that include inhibition of K(IR) and K(V) potassium currents and elevations of intracellular calcium. These responses display adaptation, i.e. their magnitude diminishes in the sustained presence o...

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Detalhes bibliográficos
Main Authors: Zhao, Fang-li, Herness, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670050/
https://ncbi.nlm.nih.gov/pubmed/19047199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.165167
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