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Resynthesis of phosphatidylinositol 4,5-bisphosphate mediates adaptation of the caffeine response in rat taste receptor cells

Caffeine, a prototypic bitter stimulus, produces several physiological actions on taste receptor cells that include inhibition of K(IR) and K(V) potassium currents and elevations of intracellular calcium. These responses display adaptation, i.e. their magnitude diminishes in the sustained presence o...

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Hlavní autoři: Zhao, Fang-li, Herness, Scott
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670050/
https://ncbi.nlm.nih.gov/pubmed/19047199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.165167
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