Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells

BACKGROUND: Chemical biology approaches using small molecule inhibitors targeting specific signaling pathways are useful tools to dissect the molecular mechanisms governing stem cell differentiation and for their possible use in therapeutic interventions. METHODS: Stem cell signaling small molecule...

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Vydáno v:Stem Cells Int
Hlavní autoři: AlMuraikhi, Nihal, Ali, Dalia, Vishnubalaji, Radhakrishnan, Manikandan, Muthurangan, Atteya, Muhammad, Siyal, Abdulaziz, Alfayez, Musaad, Aldahmash, Abdullah, Kassem, Moustapha, Alajez, Nehad M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724428/
https://ncbi.nlm.nih.gov/pubmed/31534459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3041262
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