Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells

BACKGROUND: Chemical biology approaches using small molecule inhibitors targeting specific signaling pathways are useful tools to dissect the molecular mechanisms governing stem cell differentiation and for their possible use in therapeutic interventions. METHODS: Stem cell signaling small molecule...

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Detaylı Bibliyografya
Yayımlandı:Stem Cells Int
Asıl Yazarlar: AlMuraikhi, Nihal, Ali, Dalia, Vishnubalaji, Radhakrishnan, Manikandan, Muthurangan, Atteya, Muhammad, Siyal, Abdulaziz, Alfayez, Musaad, Aldahmash, Abdullah, Kassem, Moustapha, Alajez, Nehad M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724428/
https://ncbi.nlm.nih.gov/pubmed/31534459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3041262
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