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Molecular profiling of ALDH1(+) colorectal cancer stem cells reveals preferential activation of MAPK, FAK, and oxidative stress pro-survival signalling pathways

Tumour heterogeneity leads to variable clinical response and inaccurate diagnostic and prognostic assessment. Cancer stem cells (CSCs) represent a subpopulation responsible for invasion, metastasis, therapeutic resistance, and recurrence in many human cancer types. However, the true identity of colo...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Vishnubalaji, Radhakrishnan, Manikandan, Muthurangan, Fahad, Mohamed, Hamam, Rimi, Alfayez, Musaad, Kassem, Moustapha, Aldahmash, Abdullah, Alajez, Nehad M.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862598/
https://ncbi.nlm.nih.gov/pubmed/29568377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24420
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