Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity

Bone marrow mesenchymal stem cells (BMSCs) are adult multipotent stem cells that can differentiate into mesodermal lineage cells, including adipocytes and osteoblasts. However, the epigenetic mechanisms governing the lineage-specific commitment of BMSCs into adipocytes or osteoblasts are under inves...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Ali, Dalia, Chalisserry, Elna P., Manikandan, Muthurangan, Hamam, Rimi, Alfayez, Musaad, Kassem, Moustapha, Aldahmash, Abdullah, Alajez, Nehad M.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872662/
https://ncbi.nlm.nih.gov/pubmed/29731773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2379546
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