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Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity

Bone marrow mesenchymal stem cells (BMSCs) are adult multipotent stem cells that can differentiate into mesodermal lineage cells, including adipocytes and osteoblasts. However, the epigenetic mechanisms governing the lineage-specific commitment of BMSCs into adipocytes or osteoblasts are under inves...

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Bibliografiske detaljer
Udgivet i:Stem Cells Int
Main Authors: Ali, Dalia, Chalisserry, Elna P., Manikandan, Muthurangan, Hamam, Rimi, Alfayez, Musaad, Kassem, Moustapha, Aldahmash, Abdullah, Alajez, Nehad M.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872662/
https://ncbi.nlm.nih.gov/pubmed/29731773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2379546
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