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Romidepsin Promotes Osteogenic and Adipocytic Differentiation of Human Mesenchymal Stem Cells through Inhibition of Histondeacetylase Activity

Bone marrow mesenchymal stem cells (BMSCs) are adult multipotent stem cells that can differentiate into mesodermal lineage cells, including adipocytes and osteoblasts. However, the epigenetic mechanisms governing the lineage-specific commitment of BMSCs into adipocytes or osteoblasts are under inves...

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Dades bibliogràfiques
Publicat a:Stem Cells Int
Autors principals: Ali, Dalia, Chalisserry, Elna P., Manikandan, Muthurangan, Hamam, Rimi, Alfayez, Musaad, Kassem, Moustapha, Aldahmash, Abdullah, Alajez, Nehad M.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5872662/
https://ncbi.nlm.nih.gov/pubmed/29731773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/2379546
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