Epigenetic Library Screen Identifies Abexinostat as Novel Regulator of Adipocytic and Osteoblastic Differentiation of Human Skeletal (Mesenchymal) Stem Cells

The epigenetic mechanisms promoting lineage-specific commitment of human skeletal (mesenchymal or stromal) stem cells (hMSCs) into adipocytes or osteoblasts are still not fully understood. Herein, we performed an epigenetic library functional screen and identified several novel compounds, including...

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Xehetasun bibliografikoak
Argitaratua izan da:Stem Cells Transl Med
Egile Nagusiak: Ali, Dalia, Hamam, Rimi, Alfayez, Musaed, Kassem, Moustapha, Aldahmash, Abdullah, Alajez, Nehad M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: AlphaMed Press 2016
Gaiak:
Cell-Based Drug Development, Screening, and Toxicology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954455/
https://ncbi.nlm.nih.gov/pubmed/27194745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0331
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