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Epigenetic Library Screen Identifies Abexinostat as Novel Regulator of Adipocytic and Osteoblastic Differentiation of Human Skeletal (Mesenchymal) Stem Cells

The epigenetic mechanisms promoting lineage-specific commitment of human skeletal (mesenchymal or stromal) stem cells (hMSCs) into adipocytes or osteoblasts are still not fully understood. Herein, we performed an epigenetic library functional screen and identified several novel compounds, including...

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Detalles Bibliográficos
Publicado en:Stem Cells Transl Med
Main Authors: Ali, Dalia, Hamam, Rimi, Alfayez, Musaed, Kassem, Moustapha, Aldahmash, Abdullah, Alajez, Nehad M.
Formato: Artigo
Idioma:Inglês
Publicado: AlphaMed Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954455/
https://ncbi.nlm.nih.gov/pubmed/27194745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0331
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