Epigenetic Library Screen Identifies Abexinostat as Novel Regulator of Adipocytic and Osteoblastic Differentiation of Human Skeletal (Mesenchymal) Stem Cells

The epigenetic mechanisms promoting lineage-specific commitment of human skeletal (mesenchymal or stromal) stem cells (hMSCs) into adipocytes or osteoblasts are still not fully understood. Herein, we performed an epigenetic library functional screen and identified several novel compounds, including...

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Bibliografiska uppgifter
I publikationen:Stem Cells Transl Med
Huvudupphovsmän: Ali, Dalia, Hamam, Rimi, Alfayez, Musaed, Kassem, Moustapha, Aldahmash, Abdullah, Alajez, Nehad M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: AlphaMed Press 2016
Ämnen:
Cell-Based Drug Development, Screening, and Toxicology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954455/
https://ncbi.nlm.nih.gov/pubmed/27194745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0331
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