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Epigenetic Library Screen Identifies Abexinostat as Novel Regulator of Adipocytic and Osteoblastic Differentiation of Human Skeletal (Mesenchymal) Stem Cells

The epigenetic mechanisms promoting lineage-specific commitment of human skeletal (mesenchymal or stromal) stem cells (hMSCs) into adipocytes or osteoblasts are still not fully understood. Herein, we performed an epigenetic library functional screen and identified several novel compounds, including...

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Dades bibliogràfiques
Publicat a:Stem Cells Transl Med
Autors principals: Ali, Dalia, Hamam, Rimi, Alfayez, Musaed, Kassem, Moustapha, Aldahmash, Abdullah, Alajez, Nehad M.
Format: Artigo
Idioma:Inglês
Publicat: AlphaMed Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4954455/
https://ncbi.nlm.nih.gov/pubmed/27194745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5966/sctm.2015-0331
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