CDH1 and IL1-beta expression dictates FAK and MAPKK-dependent cross-talk between cancer cells and human mesenchymal stem cells

INTRODUCTION: Tumor microenvironment conferred by stromal (mesenchymal) stem cells (MSCs) plays a key role in tumor development, progression, and response to therapy. Defining the role of MSCs in tumorigenesis is crucial for their safe utilization in regenerative medicine. Herein, we conducted compr...

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Udgivet i:Stem Cell Res Ther
Main Authors: Al-toub, Mashael, Vishnubalaji, Radhakrishnan, Hamam, Rimi, Kassem, Moustapha, Aldahmash, Abdullah, Alajez, Nehad M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533790/
https://ncbi.nlm.nih.gov/pubmed/26204886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-015-0123-0
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