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Biotransformation of the Mycotoxin Enniatin B1 by CYP P450 3A4 and Potential for Drug-Drug Interactions

Enniatins (ENNs) are fungal secondary metabolites that frequently occur in grain in temperate climates. Their toxic potency is connected to their ionophoric character and lipophilicity. The biotransformation of ENNs predominantly takes place via cytochrome P450 3A (CYP 3A)-dependent oxidation reacti...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Metabolites
Prif Awduron: Ivanova, Lada, Denisov, Ilia G., Grinkova, Yelena V., Sligar, Stephen G., Fæste, Christiane K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724072/
https://ncbi.nlm.nih.gov/pubmed/31357617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo9080158
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