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Single-Gene Deletions Contributing to Loss of Heterozygosity in Saccharomyces cerevisiae: Genome-Wide Screens and Reproducibility
Loss of heterozygosity (LOH) is a phenomenon commonly observed in cancers; the loss of chromosomal regions can be both causal and indicative of underlying genome instability. Yeast has long been used as a model organism to study genetic mechanisms difficult to study in mammalian cells. Studying gene...
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| Published in: | G3 (Bethesda) |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Genetics Society of America
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6723133/ https://ncbi.nlm.nih.gov/pubmed/31270132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400429 |
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