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Adaptation by Loss of Heterozygosity in Saccharomyces cerevisiae Clones Under Divergent Selection

Loss of heterozygosity (LOH) is observed during vegetative growth and reproduction of diploid genotypes through mitotic crossovers, aneuploidy caused by nondisjunction, and gene conversion. We aimed to test the role that LOH plays during adaptation of two highly heterozygous Saccharomyces cerevisiae...

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Опубликовано в: :Genetics
Главные авторы: James, Timothy Y., Michelotti, Lucas A., Glasco, Alexander D., Clemons, Rebecca A., Powers, Robert A., James, Ellen S., Simmons, D. Rabern, Bai, Fengyan, Ge, Shuhua
Формат: Artigo
Язык:Inglês
Опубликовано: Genetics Society of America 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781901/
https://ncbi.nlm.nih.gov/pubmed/31371407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302411
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