Cargando...

Single-Gene Deletions Contributing to Loss of Heterozygosity in Saccharomyces cerevisiae: Genome-Wide Screens and Reproducibility

Loss of heterozygosity (LOH) is a phenomenon commonly observed in cancers; the loss of chromosomal regions can be both causal and indicative of underlying genome instability. Yeast has long been used as a model organism to study genetic mechanisms difficult to study in mammalian cells. Studying gene...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:G3 (Bethesda)
Main Authors: Hoffert, Kellyn M., Strome, Erin D.
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6723133/
https://ncbi.nlm.nih.gov/pubmed/31270132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400429
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!