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Cellular calcification induced by inorganic polyphosphate involves ATP depletion and opening of the mitochondrial permeability transition pore (mPTP)

Inorganic polyphosphate (polyP) is a linear polymer containing tens to hundreds of orthophosphate residues linked by high‐energy phosphoanhydride bonds. PolyP promotes osteocalcification and bone mineralization in both mouse and human osteoblastic cells. In the present study, we examined the molecul...

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Publicado en:FEBS Open Bio
Autores principales: Tsutsumi, Kaori, Sasase, Tatsuya
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722881/
https://ncbi.nlm.nih.gov/pubmed/31325410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12703
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