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Inorganic polyphosphate (polyP) as an activator and structural component of the mitochondrial permeability transition pore
Mitochondrial permeability transition pore (mPTP) is a large channel located in the mitochondrial inner membrane. The opening of mPTP during pathological calcium overload leads to the membrane depolarization and disruption of ATP production. mPTP activation has been implicated as a central event dur...
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| Опубликовано в: : | Biochem Soc Trans |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7088465/ https://ncbi.nlm.nih.gov/pubmed/26862181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20150206 |
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