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Inorganic polyphosphate (polyP) as an activator and structural component of the mitochondrial permeability transition pore

Mitochondrial permeability transition pore (mPTP) is a large channel located in the mitochondrial inner membrane. The opening of mPTP during pathological calcium overload leads to the membrane depolarization and disruption of ATP production. mPTP activation has been implicated as a central event dur...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochem Soc Trans
Egile Nagusiak: Solesio, Maria E., Elustondo, Pia A., Zakharian, Eleonora, Pavlov, Evgeny V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7088465/
https://ncbi.nlm.nih.gov/pubmed/26862181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20150206
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