Mitochondrial permeability transition pore induction is linked to formation of the complex of ATPase C-subunit, polyhydroxybutyrate and inorganic polyphosphate

Mitochondrial permeability transition pore (mPTP) opening allows free movement of ions and small molecules leading to mitochondrial membrane depolarization and ATP depletion that triggers cell death. A multi-protein complex of the mitochondrial ATP synthase has an essential role in mPTP. However, th...

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Vydáno v:Cell Death Discov
Hlavní autoři: Elustondo, P A, Nichols, M, Negoda, A, Thirumaran, A, Zakharian, E, Robertson, G S, Pavlov, E V
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5137186/
https://ncbi.nlm.nih.gov/pubmed/27924223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.70
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