Φορτώνει......
Expression Kinetics and Innate Immune Response after Electroporation and LNP-Mediated Delivery of a Self-Amplifying mRNA in the Skin
In this work, we studied the expression kinetics and innate immune response of a self-amplifying mRNA (sa-RNA) after electroporation and lipid-nanoparticle (LNP)-mediated delivery in the skin of mice. Intradermal electroporation of the sa-RNA resulted in a plateau-shaped expression, with the plateau...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Ther Nucleic Acids |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society of Gene & Cell Therapy
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6722285/ https://ncbi.nlm.nih.gov/pubmed/31472371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.08.001 |
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