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Ligand Binding Dynamics for Pre-dimerised G Protein-Coupled Receptor Homodimers: Linear Models and Analytical Solutions

Evidence suggests that many G protein-coupled receptors (GPCRs) are bound together forming dimers. The implications of dimerisation for cellular signalling outcomes, and ultimately drug discovery and therapeutics, remain unclear. Consideration of ligand binding and signalling via receptor dimers is...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Bull Math Biol
Egile Nagusiak: White, Carla, Bridge, Lloyd J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer US 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722261/
https://ncbi.nlm.nih.gov/pubmed/29349610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11538-017-0387-x
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