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Generalized concentration addition for ligands that bind to homodimers

Concentration addition/dose addition (CA) has proved to be a powerful tool for estimating the combined effect of mixtures that act by similar mechanisms. We earlier proposed generalized concentration addition (GCA) to deal with the inability of CA to estimate effects of mixtures above the level of t...

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Detalhes bibliográficos
Publicado no:Math Biosci
Main Authors: Webster, Thomas F., Schlezinger, Jennifer J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779138/
https://ncbi.nlm.nih.gov/pubmed/31201847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mbs.2019.108214
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