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Generalized concentration addition for ligands that bind to homodimers

Concentration addition/dose addition (CA) has proved to be a powerful tool for estimating the combined effect of mixtures that act by similar mechanisms. We earlier proposed generalized concentration addition (GCA) to deal with the inability of CA to estimate effects of mixtures above the level of t...

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Publicat a:Math Biosci
Autors principals: Webster, Thomas F., Schlezinger, Jennifer J.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779138/
https://ncbi.nlm.nih.gov/pubmed/31201847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mbs.2019.108214
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