Generalized Concentration Addition Predicts Joint Effects of Aryl Hydrocarbon Receptor Agonists with Partial Agonists and Competitive Antagonists

BACKGROUND: Predicting the expected outcome of a combination exposure is critical to risk assessment. The toxic equivalency factor (TEF) approach used for analyzing joint effects of dioxin-like chemicals is a special case of the method of concentration addition. However, the TEF method assumes that...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Howard, Gregory J., Schlezinger, Jennifer J., Hahn, Mark E., Webster, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2866683/
https://ncbi.nlm.nih.gov/pubmed/20435555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.0901312
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados