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Notch-1 Inhibition Promotes Immune Regulation in Transplantation via Treg-Dependent Mechanisms
BACKGROUND: Transplantation is the treatment of choice for many patients with end-stage organ disease. Despite advances in immunosuppression, long-term outcomes remain suboptimal, hampered by drug toxicity and immune-mediated injury, the leading cause of late graft loss. The development of therapies...
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| Опубликовано в: : | Circulation |
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| Главные авторы: | , , , , , , , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6722011/ https://ncbi.nlm.nih.gov/pubmed/31266349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.119.040563 |
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