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Ex Vivo Expansion of Human Tregs by Rabbit ATG Is Dependent on Intact STAT3-Signaling in CD4(+) T Cells and Requires the Presence of Monocytes
The addition of low, nondepleting doses of rabbit antithymocyte globulin (ATG) to human peripheral blood mononuclear cells has been shown to expand functional CD4(+)CD25(+)FoxP3(+) regulatory T cells (Tregs) in vitro. This report is the first to elucidate the exact cellular mechanisms of ATG-mediate...
Tallennettuna:
| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2012
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3777828/ https://ncbi.nlm.nih.gov/pubmed/22390202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2011.03978.x |
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