Salt Accelerates Allograft Rejection through Serum- and Glucocorticoid-Regulated Kinase-1–Dependent Inhibition of Regulatory T Cells

A high-salt diet (HSD) in humans is linked to a number of complications, including hypertension and cardiovascular events. Whether a HSD affects the immune response in transplantation is unknown. Using a murine transplantation model, we investigated the effect of NaCl on the alloimmune response in v...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Safa, Kassem, Ohori, Shunsuke, Borges, Thiago J., Uehara, Mayuko, Batal, Ibrahim, Shimizu, Tetsunosuke, Magee, Ciara N., Belizaire, Roger, Abdi, Reza, Wu, Chuan, Chandraker, Anil, Riella, Leonardo V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2015
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587703/
https://ncbi.nlm.nih.gov/pubmed/25833841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014090914
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