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Targeting CCK2R for pancreatic cancer chemoprevention
Gastrin signaling mediated through cholecystokinin-2 receptor (CCK2R) and its down-stream molecules is altered in pancreatic cancer. CCK2R antagonists, YF476 (netazepide) and JNJ-26070109, were tested systematically for their effect on pancreatic intraepithelial neoplasia (PanIN) progression to panc...
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| Publicado no: | Mol Carcinog |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6721979/ https://ncbi.nlm.nih.gov/pubmed/31313401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.23084 |
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