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Targeting CCK2R for pancreatic cancer chemoprevention

Gastrin signaling mediated through cholecystokinin-2 receptor (CCK2R) and its down-stream molecules is altered in pancreatic cancer. CCK2R antagonists, YF476 (netazepide) and JNJ-26070109, were tested systematically for their effect on pancreatic intraepithelial neoplasia (PanIN) progression to panc...

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Detalhes bibliográficos
Publicado no:Mol Carcinog
Main Authors: Mohammed, Altaf, Janakiram, Naveena B, Suen, Chen, Stratton, Nicole, Lightfoot, Stanley, Singh, Anil, Pathuri, Gopal, Ritchie, Rebekah, Madka, Venkateshwar, Rao, Chinthalapally V
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721979/
https://ncbi.nlm.nih.gov/pubmed/31313401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.23084
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